网站标志
导航菜单
购物车
购物车 0 件商品 | 查看购物车 | 我的订单 | 我的积分 | 会员中心
当前日期时间
当前时间:
商品搜索
商品搜索:
价格
点评详情
点评详情
发布于:2018-8-8 19:05:22  访问:4 次 回复:0 篇
版主管理 | 推荐 | 删除 | 删除并扣分
Urium sopB mutant causes diarrhea and intestinal lesions at wild-type levels
To determine whether or not SopB, SopE2, SopA, SopD, and SipA act in concert during oral infection of calves, groups of 4 calves had been inoculated orally with strain IR715 (wild variety), ZA10 (sipA), ZA19 (sopA), ZA17 (sopD), ZA9 (sopE2), or ZA21 (sipAsopABDE2) by Oprozomib purchase utilizing a dose of 1 1010 CFU/animal. Infection of calves with all the wild sort (IR715), the sopE2 mutant (ZA9), or the sopA mutant (ZA19) induced aqueous diarrhea with feces containing numerous combinations of blood, fibrin, and mucus at day 1 SN-38 MedChemExpress postinfection (Fig. 5). All calves infected together with the Salmonella serotype Typhimurium wild sort (IR715) were euthanized among 24 and 72 h postinfection, since they had indicators of terminal illness, for example extreme anorexia and an inability to stand. Similarly, infection with all the sopE2 mutant (ZA9) or the sopA mutant (ZA19) caused lethal morbidity in all calves; on the other hand, the time for you to death was delayed in comparison with the time of death of animals infected together with the wild variety (IR715). The severity of diarrhea was decreased in calves infected together with the sopD mutant (ZA17), while calves infected with all the sipA mutant (ZA10) or the sipAsopABDE2 quintuple mutant (ZA21) had only mild transient diarrhea using a delayed onset (starting on day 2 or three postinfection). While the sipA mutant (ZA10) and also the sopD mutant (ZA17) brought on lethal morbidity in three of 4 calves, the sipAsopABDE2 quintuple mutant (ZA21) brought on lethal morbidity only in 1 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26262685 of 4 calves. The information obtained with ZA10, the sipA mutant utilised all through this study, have been notVOL. 70,SPI1 EFFECTOR PROTEINS TRIGGERING DIARRHEAFIG. six. Alter inside the plasma sodium concentration during oral infection of calves with Salmonella serotype Typhimurium strains. The graph shows the difference in the plasma sodium concentration among a sample collected on day 2 postinfection and also a preinfection sample. Solid circles indicate that the plasma sodium concentration on day 2 postinfection was beneath the typical range. The open circle indicates that the plasma sodium concentration on day 2 postinfection was within the typical range. WT, wild sort.identical towards the data obtained previously using a distinctive Salmonella serotype Typhimurium sipA mutant, strain JLR137 (48). The severity of diarrhea was lowered in calves infected using the sopD mutant (ZA17), while calves infected with the sipA mutant (ZA10) or the sipAsopABDE2 quintuple mutant (ZA21) had only mild transient diarrhea having a delayed onset (starting on day 2 or 3 postinfection). Although the sipA mutant (ZA10) and the sopD mutant (ZA17) caused lethal morbidity in 3 of 4 calves, the sipAsopABDE2 quintuple mutant (ZA21) caused lethal morbidity only in 1 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26262685 of 4 calves. The data obtained with ZA10, the sipA mutant utilised throughout this study, have been notVOL. 70,SPI1 EFFECTOR PROTEINS TRIGGERING DIARRHEAFIG. 6. Modify in the plasma sodium concentration throughout oral infection of calves with Salmonella serotype Typhimurium strains. The graph shows the difference within the plasma sodium concentration between a sample collected on day two postinfection along with a preinfection sample. Strong circles indicate that the plasma sodium concentration on day two postinfection was beneath the standard range.
共0篇回复 每页10篇 页次:1/1
共0篇回复 每页10篇 页次:1/1
我要回复
回复内容
验 证 码
看不清?更换一张
匿名发表 
脚注信息
Copyright (C) 2015-2016 All Rights Reserved. 光明云南石斛商城管理系统 版权所有   滇ICP备11005439号-1
服务时间:周一至周日 09:00 — 18:00  全国订购及服务热线:0691-5161027 
联系地址:云南省西双版纳傣族自治州勐海县工业园区   邮政编码:666200